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2月 18

Selected original publications 2014

Selected original publications
2014年(平成26年)

Kawakami Yutaka Combination immunotheapy based on the cancer cell’s characteristics and patients’ immune status. In recent advances in cancer immunotherapy, Eds, Sakaguchi S, Wolchok JD, Heike Y, Kanakura Y, Kawakami Y, Sugiyama H, Princess Takamutsu Cancer Research Fund, Tokyo. :18-22,2014

Fujita Y, Okamoto M, Goda H, Tano T, Nakashiro K, Sugita A, Fujita T, Koido S, Homma S, Kawakami Y, Hamakawa H. Prognostic significance of interleukin-8 and CD163-positive cell-infiltration in tumor tissues in patients with oral squamous cell carcinoma.PLoS One. 9(12):e110378,2014


Ohmura G, Tsujikawa T, Yaguchi T, Kawamura N, Mikami S, Sugiyama J, Nakamura K, Kobayashi A, Iwata T, Nakano H, Shimada T, Hisa Y, Kawakami Y. Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC.Mol Cancer Res. 13(4):721-31,2014

Ktano I, Ito R, Kamisako T, Eto T, Ogura T, Kawai K, Suemizu H, Takahashi T, Kawakami Y, Ito M. NOD-Rag2null IL-2Rγnull mice: an alternative to NOG mice for generation of humanized mice.Exp Anim. 63(3):321-30,2014

Hazama S, Takenouchi H, Tsunedomi R, Iida M, Suzuki N, Iizuka N, Inoue Y, Sakamoto K, Nakao M, Shindo Y, Kanekiyo S, Tokumitsu Y, Yoshimura K, Maeda N, Maeda K, Maeda Y, Matsui H, Yoshino S, Nakamura Y, Fujita Y, Hamamoto Y, Okamoto M, Fujita T, Kawakami Y, Oka M. Predictive Biomarkers for the Outcome of Vaccination of Five Therapeutic Epitope Peptides for Colorectal Cancer. Anticancer Res. 34(8):4201-4206,2014

Saito K, IizukaY, Ohta S, Takahashi S, Nakamura K, Saya H, Yoshida K, Kawakami Y, Toda M.  Functional analysis of a novel glioma antigen, EFTUD1. Neuro-Oncology. 16(12):1618-1629,2014

Hazama S, Nakamura Y, Tanaka H, Hirakawa K, Tahara K, Shimizu R, Ozasa H, Etoh R, Sugiura F, Okuno K, Furuya T, Nishimura T, Sakata K, Yoshimatsu K, Takenouchi H, Tsunedomi R, Inoue Y, Kanekiyo S, Shindo Y, Suzuki N, Yoshino S, Shinozaki H, Kamiya A, Furukawa H, Yamanaka T, Fujita T, Kawakami Y, Oka M.  A phase ΙI study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study). J Transl Med.  12(1):108,2014


Nishio H, Yaguchi T, Sugiyama J, Sumimoto H, Umezawa K, Iwata T, Susumu N, Fujii T, Kawamura N, Kobayashi A, Park J, Aoki D, Kawakami Y. Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor. Br J Cancer. 110(12):2965-74,2014

Sébastien Abad, Grégoire Wieërs, Didier Colau, Claude Wildmann, Emmanuelle Delair, Robin Dhote, Antoine P. Brézin, Yukata Kawakami, Pierre G. Coulie, Pierre van der Bruggen. Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient . Molecular Vision. 20:956-969,2014

Iwata T, Fujii T, Morii K, Saito M, Sugiyama J, Nishio H, Morisada T, Tanaka K, Yaguchi T, Kawakami Y, Aoki D. Cytokine profile in cervical mucosa of Japanese patients with cervical intraepithelial neoplasia. Int J Clin Oncol.  [Epub ahead of print]:,2014

Ohta S, Veraitch O, Okano H, Ohyama M, Kawakami Y. The Potential of Using Induced Pluripotent Stem Cells in Skin Diseases. in “Cell and  Molecular Biology and Imaging of Stem Cells” Eds, Heide Schatten: John Wiley & Sons, Inc.Chapter 10:223-245,2014

Kawamura N, Udagawa M, Fujita T, Sakurai T, Yaguchi T, Kawakami Y. Intratumoral Injection of BCG-CWS-Pretreated Dendritic Cells Following Tumor Cryoablation.in “Cancer Vaccines Methods and Protocols”  Eds, Michael J.P., Patricia D. : Human Press. Methods in Molecular Biology, Vol. 1139:145-153,2014


Kudo-Sait C, Masahiro Yura, Ryusuke Yamamoto Kawakami Y.  Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H Cancer Res. 74(5):1361-70,2014

Nakamura S, Yaguchi T, Kawamura N, Kobayashi A, Sakurai T, Higuchi H, Takaishi H, Hibi T, Kawakami Y. TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression. J Immunother. 37(2):63-72,2014

Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci DV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D’Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Shaw PA, Clarke BA, Wouters BG, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato S, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Ascierto PA, Marincola FM, Fox BA, Pagès F. Towards the introduction of the Immunoscore in the classification of malignant tumors. J Pathol. 232:199-209,2014